While you can see your self-image just fine in Photo Booth and you can take nice video clips, this is where it ends. I am running the current/latest version of Mac OS X, Version 10.5.5, 2 x 2.66 GHz Dual Core Intel Xeon, 8 GB DRAM. Unfortunately, this webcam with mic device has HUGE compatibility problems right now with the Mac Pro. It is quite pricey at $129, because it is supposedly so 'good,' with features such as 'Right Light 2,' and its excellent optics.
I just purchased the MAC compatible “Logitech QuickCam Vision Pro” webcam.